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The endoplasmic reticulum membrane protein Sec62 as potential therapeutic target in SEC62 overexpressing tumors

The human SEC62 gene is located on chromosome 3q, was characterized as a tumor driver gene and is found to be overexpressed in an ever-growing number of tumors, particularly those with 3q26 amplification. Where analyzed, SEC62 overexpression was associated with poor prognosis. Sec62 protein is a mem...

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Autors principals: Julia S. M. Zimmermann, Johannes Linxweiler, Julia C. Radosa, Maximilian Linxweiler, Richard Zimmermann
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-10-01
Col·lecció:Frontiers in Physiology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fphys.2022.1014271/full
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