The Hippo pathway in clear cell renal cell carcinoma (ccRCC): a nexus with the VHL disruption?

Background: Clear cell renal cell carcinoma (ccRCC) represents 70% of kidney cancers, with 20–50% recurrence risk after surgery. Despite therapeutic advances, no reliable biomarkers have been identified for patient stratification or treatment response prediction. While VHL gene alterations are well-...

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Principais autores:	T Waeckel, R Lefranc, M Waeckel, M Riffet, X Tillou, G Levallet, C Bazille
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2026-04-01
叢編:	Translational Oncology
主題:	Clear cell renal cell carcinoma VHL Hippo pathway Biomarker Emerging therapeutic strategy
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S1936523326000586
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