Local Colonic Administration of a Serine Protease Inhibitor Improves Post-Inflammatory Visceral Hypersensitivity in Rats

Dysregulation of the protease–antiprotease balance in the gastrointestinal tract has been suggested as a mechanism underlying visceral hypersensitivity in conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). We aimed to study the potential therapeutic role of an in...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Nikita Hanning, Michelle De bruyn, Hannah Ceuleers, Tim Boogaerts, Maya Berg, Annemieke Smet, Heiko U. De Schepper, Jurgen Joossens, Alexander L. N. van Nuijs, Joris G. De Man, Koen Augustyns, Ingrid De Meester, Benedicte Y. De Winter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-05-01
coleção:	Pharmaceutics
Assuntos:	elastase irritable bowel syndrome proteolytic activity serine proteases trypsin visceral hypersensitivity
Acesso em linha:	https://www.mdpi.com/1999-4923/13/6/811
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!