NDRG1 upregulation by ubiquitin proteasome system dysfunction aggravates neurodegeneration
Abstract Protein turnover is crucial for cell survival, and the impairment of proteostasis leads to cell death. Aging is associated with a decline in proteostasis, as the progressive accumulation of damaged proteins is a hallmark of age-related disorders such as neurodegenerative diseases, including...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2024-10-01
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| Series: | Molecular Brain |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s13041-024-01150-1 |
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