Mechanistic insights into the conversion of flavin adenine dinucleotide (FAD) to 8-formyl FAD in formate oxidase: a combined experimental and in-silico study

Abstract Formate oxidase (FOx), which contains 8-formyl flavin adenine dinucleotide (FAD), exhibits a distinct advantage in utilizing ambient oxygen molecules for the oxidation of formic acid compared to other glucose-methanol-choline (GMC) oxidoreductase enzymes that contain only the standard FAD c...

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Bibliografske podrobnosti

Principais autores:	Kai Wen, Sirui Wang, Yixin Sun, Mengsong Wang, Yingjiu Zhang, Jingxuan Zhu, Quanshun Li
Format:	Artigo
Jezik:	Inglês
Izdano:	SpringerOpen 2024-07-01
Serija:	Bioresources and Bioprocessing
Teme:	Formate oxidase 8-Formyl flavin adenine dinucleotide Oxidative maturation Molecular dynamics simulation QM/MM umbrella sampling simulation
Online dostop:	https://doi.org/10.1186/s40643-024-00782-4
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