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ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway

Abstract Background Osteosarcoma is a diverse and aggressive bone tumor. Driver genes regulating osteosarcoma initiation and progression remains incompletely defined. Zinc finger protein 692 (ZNF692), a kind of Krüppel C2H2 zinc finger transcription factor, exhibited abnormal expression in different...

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Principais autores: Di Zheng, Zhun Wei, Chong Zhang, Wenda Liu, Changtian Gong, Fei Wu, Weichun Guo
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-04-01
Serier:Biology Direct
Fag:
ZNF692
Osteosarcoma
MEK/ERK pathway
TNK2
Proliferation
Online adgang:https://doi.org/10.1186/s13062-024-00472-3
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