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Mesenchymal stem cell-derived exosomal mir-21-5p inhibits YAP1 expression and improves outcomes in myocardial infarction

Abstract Background Myocardial infarction (MI) remains a significant global health concern, characterized by cardiomyocyte apoptosis and adverse ventricular remodeling. Nevertheless, the interplay between exosomal miR-21-5p and Yes-associated protein 1 (YAP1) in the context of MI remains unexplored....

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Principais autores: Zhou Ji, Chan Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-10-01
Serier:BMC Cardiovascular Disorders
Fag:
miR-21-5p
YAP1
MSC exosome
Inflammation
Apoptosis
MI
Online adgang:https://doi.org/10.1186/s12872-024-04197-z
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