Transforming the CRISPR/dCas9-based gene regulation technique into a forward screening tool in Plasmodium falciparum

Summary: It is a significant challenge to assess the functions of many uncharacterized genes in human malaria parasites. Here, we present a genetic screening tool to assess the contribution of essential genes from Plasmodium falciparum by the conditional CRISPR-/deadCas9-based interference and activ...

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Autores principales:	Amuza Byaruhanga Lucky, Chengqi Wang, Xiaolian Li, Xiaoying Liang, Azhar Muneer, Jun Miao
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2024-04-01
Colección:	iScience
Materias:	Genetics Techniques in genetics Parasitology Genomic analysis
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2589004224008241
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