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Ectopic USP15 expression inhibits HIV-1 transcription involving changes in YY1 deubiquitination and stability

IntroductionProtein homeostasis is maintained by the opposing action of ubiquitin ligase and deubiquitinase, two important components of the ubiquitin-proteasome pathway, and contributes to both normal physiological and pathophysiological processes. The current study aims to delineate the roles of u...

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Hauptverfasser: Sahar Rezaei, Khalid A. Timani, Ying Liu, Johnny J. He
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-11-01
Schriftenreihe:Frontiers in Cellular and Infection Microbiology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1371655/full
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