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Association of gene polymorphisms in FBN1 and TGF-β signaling with the susceptibility and prognostic outcomes of Stanford type B aortic dissection

Abstract Background This study is aimed at investigating the association of Fibrillin-1 (FBN1) and transforming growth factor β (TGF-β) signaling-related gene polymorphisms with the susceptibility of Stanford type B aortic dissection (AD) and its clinical prognostic outcomes. Methods Five single-nuc...

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Principais autores: Ling Sun, Yafei Chang, Peipei Jiang, Yitong Ma, Qinghua Yuan, Xiang Ma
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-03-01
coleção:BMC Medical Genomics
Assuntos:
Aortic dissection
FBN1
TGFB1
TGFB2
SNP
GMDR
Acesso em linha:https://doi.org/10.1186/s12920-022-01213-z
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