Long non-coding RNA-NONMMMUT004552.2 regulates the unloading-induced bone loss through the miRNA-15b-5p/Syne1 in mice

Abstract Exercise-induced mechanical loading can increase bone strength whilst mechanical unloading enhances bone-loss. Here, we investigated the role of lncRNA NONMMUT004552.2 in unloading-induced bone-loss. Knockout of lncRNA NONMMUT004552.2 in hindlimb-unloaded mice caused an increase in the bone...

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Detalles Bibliográficos

Autores principales:	Zheng Zhang, Yu Jing, Ang Zhang, JiShan Liu, Heming Yang, Xiaotong Lou, Liyan Xu, Min Liu, Yikun Zhang, Jianwen Gu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2024-03-01
Colección:	npj Microgravity
Acceso en línea:	https://doi.org/10.1038/s41526-024-00382-8
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