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Evidence for Increased Expression of SIRT3 Associated with Hyperandrogenism in Granulosa Cells of Non-Obese PCOS Patients

Background: SIRT3 regulates the generation of reactive oxygen species (ROS) in human granulosa cells (GCs). Increased levels of oxidative stress may cause follicular dysplasia in GCs of polycystic ovary syndrome (PCOS) patients. However, expression and regulation of SIRT3 in GCs of PCOS patients hav...

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Hlavní autoři: Shen Zhang, Wenli Deng, Qiongyou Liu, Wei Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: IMR Press 2022-11-01
Edice:Clinical and Experimental Obstetrics & Gynecology
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On-line přístup:https://www.imrpress.com/journal/CEOG/49/11/10.31083/j.ceog4911256
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