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Astragaloside IV alleviates inflammation and improves myocardial metabolism in heart failure mice with preserved ejection fraction

BackgroundHeart failure with preserved ejection fraction (HFpEF) has grown to become the dominant form of heart failure worldwide. However, no unequivocally effective treatment for HFpEF has been identified in clinical trials. In this study, we report that Astragaloside IV (AS-IV) can be used to tre...

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Principais autores: Xiao Wang, Xinting Chen, Yuting Wang, Xinyu He, Lan Li, Xiaodan Wang, Yuting Huang, Guanwei Fan, Jingyu Ni
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-11-01
Serier:Frontiers in Pharmacology
Fag:
HFpEF
astragaloside IV
inflammation
metabolism
mitochondria
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1467132/full
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