The role of heat shock proteins in preventing amyloid toxicity
The oligomerization of monomeric proteins into large, elongated, β-sheet-rich fibril structures (amyloid), which results in toxicity to impacted cells, is highly correlated to increased age. The concomitant decrease of the quality control system, composed of chaperones, ubiquitin-proteasome system a...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Molecular Biosciences |
| Assuntos: | |
| Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.1045616/full |
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