Case Report: Treatment of refractory lung disease in systemic juvenile idiopathic arthritis with cyclophosphamide and rituximab combination therapy

IntroductionSystemic juvenile idiopathic arthritis-associated lung disease (sJIA-LD) is a rare, potentially fatal complication of sJIA, often accompanied by pulmonary hypertension (PHTN) and macrophage activation syndrome (MAS). The underlying pathophysiology remains poorly understood and optimal ma...

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Bibliografische Detailangaben

Hauptverfasser:	William J. Freeman, Eileen C. Rife, Randy Q. Cron
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-05-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	case report combination therapy cyclophosphamide lung disease macrophage activation syndrome pulmonary hypertension
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1798455/full
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