Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces.

Interactions of influenza A virus (IAV) with sialic acid (SIA) receptors determine viral fitness and host tropism. Binding to mucus decoy receptors and receptors on epithelial host cells is determined by a receptor-binding hemagglutinin (HA), a receptor-destroying neuraminidase (NA) and a complex in...

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Hlavní autoři:	Hongbo Guo, Huib Rabouw, Anne Slomp, Meiling Dai, Floor van der Vegt, Jan W M van Lent, Ryan McBride, James C Paulson, Raoul J de Groot, Frank J M van Kuppeveld, Erik de Vries, Cornelis A M de Haan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2018-08-01
Edice:	PLoS Pathogens
On-line přístup:	http://europepmc.org/articles/PMC6107293?pdf=render
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