Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from <i>Plasmodium</i> Challenge in a Mouse Model

The need for a malaria vaccine is indisputable. A single vaccine for <i>Plasmodium</i> pre-erythrocytic stages targeting the major sporozoite antigen circumsporozoite protein (CSP) has had partial success. Additionally, CD8+ T cells targeting liver-stage (LS) antigens induced by live attenuated spor...

Descrición completa

Detalles Bibliográficos

Principais autores:	Sophia M. Reeder, Emma L. Reuschel, Mamadou A. Bah, Kun Yun, Nicholas J. Tursi, Kevin Y. Kim, Jacqueline Chu, Faraz I. Zaidi, Ilknur Yilmaz, Robert J. Hart, Benjamin Perrin, Ziyang Xu, Laurent Humeau, David B. Weiner, Ahmed S. I. Aly
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-01-01
Series:	Vaccines
Assuntos:	malaria <i>plasmodium</i> liver stage exported proteins dna vaccines
Acceso en liña:	https://www.mdpi.com/2076-393X/8/1/21
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!