Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a poor prognosis, despite surgical resection combined with radio- and chemotherapy. The major clinical obstacles contributing to poor GBM prognosis are late diagnosis, diffuse infiltration, pseudo-palisading necrosis, micr...

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Bibliographic Details

Main Authors:	Syreeta DeCordova, Abhishek Shastri, Anthony G. Tsolaki, Hadida Yasmin, Lukas Klein, Shiv K. Singh, Uday Kishore
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2020-07-01
Series:	Frontiers in Immunology
Subjects:	glioblastoma microenvironment brain tumor immunity microglia astrocytes
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.01402/full
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