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The impact of dose rate optimisation and robust optimisation on FLASH proton therapy treatment plan quality and dose rates

Background and purposeBragg peak FLASH proton therapy (FLASH-PT) relies on fast dose delivery (≥ 40 Gy/s) to elicit a normal tissue sparing effect. FLASH-PT beam delivery modifications lead to inferior margin-based FLASH-PT treatment plan quality compared to intensity modulated proton therapy (IMPT)...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Nathalie Lövgren, Rasmus Nilsson, Erik Traneus, Kristoffer Petersson
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2025-12-01
Schriftenreihe:Frontiers in Oncology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fonc.2025.1638319/full
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