Colonic Leucine-Rich Repeat Kinase 2 Expression Is Increased and Associated With Disease Severity in Patients With Parkinson’s Disease

BackgroundMutations in leucine-rich repeat kinase 2 (LRRK2) comprise a common genetic risk factor for Parkinson’s disease (PD) and inflammatory bowel disease (IBD). We investigated the expression of LRRK2 in colonic biopsies obtained from a cohort of PD patients and healthy controls.MethodsA cohort...

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Egile Nagusiak:	Peng-Hsiang Liao, Han-Lin Chiang, Chia-Tung Shun, Jen-Fan Hang, Han-Mo Chiu, Ming-Shiang Wu, Chin-Hsien Lin
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2022-01-01
Saila:	Frontiers in Aging Neuroscience
Gaiak:	Parkinson’s disease colon biopsy leucine-rich repeat kinase 2 inflammatory bowel diseases biomarker (BM)
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fnagi.2021.819373/full
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