Increased levels of α2-3- and α2-6-linked sialic acids during airway inflammation govern influenza A binding to peripheral airway mucins in a subtype-dependent manner

BackgroundInfluenza infection increases the risk of pneumonia and respiratory failure in chronic obstructive pulmonary disease (COPD) and mucins play an important role in pulmonary host defense.MethodsLower airway mucins were obtained from long-term smokers with and without COPD, pneumonia patients,...

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Үндсэн зохиолчид:	John Benktander, Macarena Paz Quintana Hayashi, Rickard Nordén, Lisa Pettersson, Magnus Paulsson, Anders Lindén, Sara K. Lindén
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-03-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	BAL influenza A virus inhibition lung mucins O-glycan
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1768280/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!