Impact of age‐dependent red blood cell parameters on α‐globin gene genotyping in children

Abstract When screening for α‐thalassemia in children, adult cut‐offs for mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) are generally applied to guide genetic evaluation. However, the normal ranges for MCV and MCH are lower in children than in adults, so we hypothesized that us...

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Hauptverfasser:	Peter H. Nissen, Helene Narvestad‐Bøttger, Helle Pilgaard Kristensen, Anne Winther‐Larsen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2023-02-01
Schriftenreihe:	eJHaem
Schlagworte:	alpha‐thalassemia genetic evaluation hemoglobin A2 mean corpuscular hemoglobin mean corpuscular volume screening
Online-Zugang:	https://doi.org/10.1002/jha2.627
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