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Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening

N-myristoyltransferase (NMT) inhibitors that were initially developed for treatment of parasitic protozoan infections, including sleeping sickness, malaria, and leismaniasis, have also shown great promise as treatment for oncological diseases. The successful transition of NMT inhibitors, which are c...

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Principais autores: Danislav S. Spassov, Mariyana Atanasova, Irini Doytchinova
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2022-08-01
סדרה:Molecules
נושאים:
NMT
N-myristoyltransferase inhibitor
myristoylation
virtual screening
ZINC database
salt bridge in ligand-protein complexes
גישה מקוונת:https://www.mdpi.com/1420-3049/27/17/5478
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