An SETD1A/Wnt/β-catenin feedback loop promotes NSCLC development

Abstract Background SETD1A, a member of SET1/MLL family H3K4 methyltransferases, is involved in the tumorigenesis of numerous cancers. However, the biological role and mechanism of SETD1A in non-small cell lung cancer (NSCLC) remain to be elucidated. Methods The expression of SETD1A, NEAT1, EZH2, an...

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Hlavní autoři:	Rui Wang, Jian Liu, Kai Li, Ganghua Yang, Sisi Chen, Jie Wu, Xinming Xie, Hong Ren, Yamei Pang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-10-01
Edice:	Journal of Experimental & Clinical Cancer Research
Témata:	SETD1A β-Catenin NEAT1 EZH2 NSCLC
On-line přístup:	https://doi.org/10.1186/s13046-021-02119-x
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