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Analysis of Upstream Regulators, Networks, and Pathways Associated With the Expression Patterns of Polycystic Ovary Syndrome Candidate Genes During Fetal Ovary Development

Polycystic Ovary Syndrome (PCOS) is a multifactorial syndrome with reproductive, endocrine, and metabolic symptoms, affecting about 10% women of reproductive age. Pathogenesis of the syndrome is poorly understood with genetic and fetal origins being the focus of the conundrum. Genetic predisposition...

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Principais autores: Rafiatu Azumah, Katja Hummitzsch, Monica D. Hartanti, Justin C. St. John, Richard A. Anderson, Raymond J. Rodgers
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-02-01
coleção:Frontiers in Genetics
Assuntos:
polycystic ovary syndrome
mitochondrial dysfunction
stromal expansion
steroidogenesis
upstream regulators
fetal ovary
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2021.762177/full
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