Activation of neuronal N-methyl-d-aspartate receptor plays a pivotal role in Japanese encephalitis virus-induced neuronal cell damage

Abstract Background Overstimulation of glutamate receptors, especially neuronal N-methyl-d-aspartate receptor (NMDAR), mediates excitatory neurotoxicity in multiple neurodegenerative diseases. However, the role of NMDAR in the regulation of Japanese encephalitis virus (JEV)-mediated neuropathogenesi...

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Bibliografische Detailangaben

Hauptverfasser:	Zheng Chen, Xugang Wang, Usama Ashraf, Bohan Zheng, Jing Ye, Dengyuan Zhou, Hao Zhang, Yunfeng Song, Huanchun Chen, Shuhong Zhao, Shengbo Cao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2018-08-01
Schriftenreihe:	Journal of Neuroinflammation
Schlagworte:	JEV NMDAR Activation MK-801 Neuronal death
Online-Zugang:	http://link.springer.com/article/10.1186/s12974-018-1280-8
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