Extrapolation of Survival Data Using a Bayesian Approach: A Case Study Leveraging External Data from Cilta-Cel Therapy in Multiple Myeloma

Abstract Introduction Extrapolating long-term overall survival (OS) from shorter-term clinical trial data is key to health technology assessment in oncology. However, extrapolation using conventional methods is often subject to uncertainty. Using ciltacabtagene autoleucel (cilta-cel), a chimeric ant...

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Auteurs principaux:	Stephen Palmer, Yi Lin, Thomas G. Martin, Sundar Jagannath, Andrzej Jakubowiak, Saad Z. Usmani, Nasuh Buyukkaramikli, Hilary Phelps, Rafal Slowik, Feng Pan, Satish Valluri, Lida Pacaud, Graham Jackson
Format:	Artigo
Langue:	Inglês
Publié:	Adis, Springer Healthcare 2023-06-01
Collection:	Oncology and Therapy
Sujets:	Ciltacabtagene autoleucel Relapsed/refractory multiple myeloma Overall survival Extrapolation
Accès en ligne:	https://doi.org/10.1007/s40487-023-00230-x
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