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Insight into the mitochondrial unfolded protein response and cancer: opportunities and challenges

Abstract The mitochondrial unfolded protein response (UPRmt) is an evolutionarily conserved protective transcriptional response that maintains mitochondrial proteostasis by inducing the expression of mitochondrial chaperones and proteases in response to various stresses. The UPRmt-mediated transcrip...

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Bibliografische Detailangaben
Hauptverfasser: Ge Wang, Yumei Fan, Pengxiu Cao, Ke Tan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-02-01
Schriftenreihe:Cell & Bioscience
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Online-Zugang:https://doi.org/10.1186/s13578-022-00747-0
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