The Impact of QSP Modeling on the Design and Optimization of Gene Therapy Approaches
ABSTRACT Quantitative Systems Pharmacology (QSP) is increasingly utilized to support the design and translation of gene therapies. This perspective outlines the application of QSP modeling across three domains of gene therapy: mRNA‐based therapeutics, adeno‐associated virus (AAV) vectors, and genome...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley
2025-11-01
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| Schriftenreihe: | CPT: Pharmacometrics & Systems Pharmacology |
| Online-Zugang: | https://doi.org/10.1002/psp4.70131 |
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