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SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians.

Planarian flatworms are able to both regenerate their whole bodies and continuously adapt their size to nutrient status. Tight control of stem cell proliferation and differentiation during these processes is the key feature of planarian biology. Here we show that the planarian homolog of the phospho...

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Principais autores: Cristina González-Estévez, Daniel A Felix, Matthew D Smith, Jordi Paps, Simon J Morley, Victoria James, Tyson V Sharp, A Aziz Aboobaker
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS Genetics
Online adgang:https://doi.org/10.1371/journal.pgen.1002619
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