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Angled Insertion of Microneedles for Targeted Antigen Delivery to the Epidermis

Peanut and tree nut allergies account for most food-induced anaphylactic events. The standard allergy immunotherapy approach involves subcutaneous injection, which is challenging because severe adverse reactions can occur when antigens spread systemically. Allergen localization within the epidermis...

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Autori principali: Rohan Murty, Abishek Sankaranarayanan, Isabella I. Bowland, Juan Mena-Lapaix, Mark R. Prausnitz
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-02-01
Serie:Pharmaceutics
Soggetti:
coated microneedle patch
targeted drug delivery
skin epidermis
allergy immunotherapy
peanut protein
optical coherence tomography
Accesso online:https://www.mdpi.com/1999-4923/14/2/347
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