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Role of endothelial microRNA 155 on capillary leakage in systemic inflammation

Abstract Background Capillary leakage is a key contributor to the pathological host response to infections. The underlying mechanisms remain incompletely understood, and the role of microRNAs (MIR) has not been investigated in detail. We hypothesized that specific MIRs might be regulated directly in...

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Principais autores: Valerie Etzrodt, Temitayo O. Idowu, Heiko Schenk, Benjamin Seeliger, Antje Prasse, Kristina Thamm, Thorben Pape, Janina Müller-Deile, Matijs van Meurs, Thomas Thum, Ankita Garg, Robert Geffers, Klaus Stahl, Samir M. Parikh, Hermann Haller, Sascha David
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2021-02-01
coleção:Critical Care
Assuntos:
Tight junctions
Respiratory distress syndrome
MicroRNAs
Endothelium
Sepsis
Acesso em linha:https://doi.org/10.1186/s13054-021-03500-0
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