Efficacy of CMX001 as a Post Exposure Antiviral in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

CMX001, a lipophilic nucleotide analog formed by covalently linking 3-(hexdecyloxy)propan-1-ol to cidofovir (CDV), is being developed as a treatment for smallpox. In the absence of human cases of smallpox, new treatments must be tested for efficacy in animal models. Previously, we demonstrated the e...

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Autori principali:	Scott Foster, Randall Lanier, Alice Robertson, Richard W. Moyer, George Painter, Bernhard Lampert, Brandi R. Manning, Stacey A. Gray, Daniele Swetnam, Andrew J. Smith, Mathew M. Adams, Greg Wallace, Scott F. Lindsey, Andrew M. Burrage, Amanda D. Rice
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2011-01-01
Serie:	Viruses
Soggetti:	poxvirus antiviral CMX001 rabbitpox smallpox treatment
Accesso online:	http://www.mdpi.com/1999-4915/3/1/47/
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