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Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling

<p>Abstract</p> <p>Background</p> <p>Pericytes are integral members of the neurovascular unit. Using mouse models lacking endothelial-secreted platelet derived growth factor-B (PDGF-B) or platelet derived growth factor receptor beta (PDGFRβ) on pericytes, it has been demonstrated that PDGF-B/PDGFRβ...

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Autori principali: Winkler Ethan A, Bell Robert D, Zlokovic Berislav V
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2010-08-01
Serie:Molecular Neurodegeneration
Accesso online:http://www.molecularneurodegeneration.com/content/5/1/32
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