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IGFBP in tumor immunity: a novel target for cancer immunotherapy

Abstract Background The insulin-like growth factor-binding protein (IGFBP) family consists of soluble bioactive molecules that, together with insulin-like growth factors (IGFs) and their receptors, are critical modulators of endocrine, metabolic, and immune functions. IGFBPs serve as signaling inter...

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Bibliographic Details
Main Authors: Qingqiang Lei, Liangbin Lin, Hui Yu
Format: Artigo
Language:Inglês
Published: BMC 2026-05-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-026-08204-z
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