THE TSH RECEPTOR GLO ASSAY -A HIGH THROUGHPUT DETECTION SYSTEM FOR THYROID STIMULATION
Background: To identify novel small molecules against the TSH receptor, we developed a sensitive transcription-based luciferase high-throughput screening (HTS) system named the TSHR-Glo Assay (TSHR-Glo). Methods: This assay uses double-transfected CHO cells stably expressing the human TSHR and a cAM...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2016-01-01
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| Schriftenreihe: | Frontiers in Endocrinology |
| Schlagworte: | |
| Online-Zugang: | http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00003/full |
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