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Adipokine chemerin overexpression in trophoblasts leads to dyslipidemia in pregnant mice: implications for preeclampsia

Abstract Background The adipokine chemerin regulates adipogenesis and the metabolic function of both adipocytes and liver. Chemerin is elevated in preeclamptic women, and overexpression of chemerin in placental trophoblasts induces preeclampsia-like symptoms in mice. Preeclampsia is known to be acco...

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Principais autores: Lunbo Tan, Zijun Ouyang, Zhilong Chen, Fen Sun, Haichun Guo, Feng Wang, Monique Mulder, Yuan Sun, Xifeng Lu, Jian V. Zhang, A. H. Jan Danser, Koen Verdonk, Xiujun Fan, Qing Yang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-01-01
Serier:Lipids in Health and Disease
Fag:
Chemerin
Preeclampsia
Dyslipidemia
Placenta
Trophoblast
Phospholipids
Online adgang:https://doi.org/10.1186/s12944-023-01777-4
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