Opacification Domain of Serum Opacity Factor Inhibits Beta-Hemolysis and Contributes to Virulence of <named-content content-type="genus-species">Streptococcus pyogenes</named-content>

ABSTRACT Serum opacity factor (SOF) is a cell surface virulence factor made by the human pathogen Streptococcus pyogenes. We found that S. pyogenes strains with naturally occurring truncation mutations in the sof gene have markedly enhanced beta-hemolysis. Moreover, deletion of the sof gene in a SOF...

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Hlavní autoři:	Luchang Zhu, Randall J. Olsen, James M. Musser
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2017-04-01
Edice:	mSphere
Témata:	beta-hemolysis Streptococcus pyogenes high-density lipoprotein serum opacity factor virulence
On-line přístup:	https://journals.asm.org/doi/10.1128/mSphereDirect.00147-17
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