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The neuropathy-linked protein TECPR2 is a Rab5 effector that regulates cargo recycling from early endosomes

Abstract Small GTP-binding proteins of the Rab, Arf, and Arf-like family mediate the recruitment of their effectors to subcellular membrane-bound compartments, which in turn mediate vesicle budding, motility, and tethering. Here, we report that Tectonin-β-propeller repeat containing protein 2 (TECPR...

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Autors principals: Sankalita Paul, Rajat Pant, Poonam Sharma, Kshitiz Walia, Suhasi Gupta, Adhil Aseem, Kamlesh Kumari Bajwa, Ruben George, Yudish Varma, Tripta Bhatia, Rajesh Ramachandran, Amit Tuli, Mahak Sharma
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-11-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-025-65568-4
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