Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial

Summary: Background: BCG vaccination prevents severe childhood tuberculosis (TB) and was introduced in South Africa in the 1950s. It is hypothesised that BCG trains the innate immune system by inducing epigenetic and functional reprogramming, thus providing non-specific protection from respiratory...

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Autori principali:	Caryn M. Upton, Rob C. van Wijk, Laurynas Mockeliunas, Ulrika S.H. Simonsson, Kirsten McHarry, Gerben van den Hoogen, Chantal Muller, Arne von Delft, Helene-Mari van der Westhuizen, Reinout van Crevel, Gerhard Walzl, Pedro M. Baptista, Jonathan Peter, Andreas H. Diacon
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-06-01
Serie:	EClinicalMedicine
Soggetti:	COVID-19 BCG Respiratory tract infection Vaccine Tuberculosis Trained immunity
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2589537022001444
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