CiRS-7 Enhances the Liquid-liquid Phase Separation of miRISC and Promotes DNA Damage Repair

ABSTRACTNoncoding RNAs have been found to play important roles in DNA damage repair, whereas the participation of circRNA remains undisclosed. Here, we characterized ciRS-7, a circRNA containing over 70 putative miR-7-binding sites, as an enhancer of miRISC condensation and DNA repair. Both in vivo...

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Auteurs principaux:	Yun-Long Wang, Li-Li Feng, Jie Shi, Wan-Ying Chen, Shu-Ying Bie, Shao-Mei Bai, Guang-Dong Zeng, Rui-Zhi Wang, Jian Zheng, Xiang-Bo Wan, Xin-Juan Fan
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis Group 2023-12-01
Collection:	Nucleus
Sujets:	CircRNA ciRS-7 condensation DNA repair liquid-liquid phase separation miRISC
Accès en ligne:	https://www.tandfonline.com/doi/10.1080/19491034.2023.2293599
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