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Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

ObjectiveAs a leading cause of cancer-related mortality, liver cancer was associated with metabolic dysregulation. We aimed to identify metabolism-related prognostic biomarkers and therapeutic targets.MethodsTranscriptomic data from TCGA were analyzed using EdgeR to identify differentially expressed...

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Principais autores: Taorui Wang, Zijun Lai, Shengjun Tang, Lehang Lin, Mingjiao Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-09-01
Serier:Frontiers in Genetics
Fag:
liver cancer
metabolism
machine learning
immune cells
therapy
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2025.1654459/full
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