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IL-10 inhibition during immunization improves vaccine-induced protection against Staphylococcus aureus infection

Staphylococcus aureus is a major human pathogen. An effective anti–S. aureus vaccine remains elusive as the correlates of protection are ill-defined. Targeting specific T cell populations is an important strategy for improving anti–S. aureus vaccine efficacy. Potential bottlenecks that remain are S....

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Sparad:
Huvudupphov: Alanna M. Kelly, Karen N. McCarthy, Tracey J. Claxton, Simon R. Carlile, Eoin C. O’Brien, Emilio G. Vozza, Kingston H.G. Mills, Rachel M. McLoughlin
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical investigation 2024-07-01
Serie:JCI Insight
Ämnen:
Immunology
Vaccines
Länkar:https://doi.org/10.1172/jci.insight.178216
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