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8-oxo-7,8-dihydroguanosine (8-oxo-Guo) drives pulmonary inflammatory pathways through pattern recognition receptors

8-oxo-7,8-dihydroguanosine (8-oxo-Guo) is a key biomarker of oxidative stress and nucleic acid damage, the levels of which positively correlate with aging and age-related diseases. Notably, in inflammatory diseases, 8-oxo-Guo levels are significantly elevated. In vivo mouse experiments showed that a...

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Autors principals: Rui Li, Jia-Xin Pan, Gang Sheng, Xu-Fan Gao, Ran Huan, Ruo-Mei Qi, Jin Li, Jian-Ping Cai
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2026-07-01
Col·lecció:Redox Biology
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2213231726002090
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