Novel Insights on Benzo[<i>b</i>]thiophene Analogues for MAO-B Inhibition and Neuroprotection: Design, Synthesis, Molecular Modelling Studies and Biological Activity

Neurodegenerative disorders (NDs), such as Alzheimer’s disease and Parkinson’s disease (PD), represent a significant challenge for ageing populations, with their prevalence increasing worldwide. Elevated human Monoamine Oxidase B (<i>h</i>MAO-B) activity has been related to neurodegenerative progres...

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Autors principals:	Francesca Arrighi, Emanuela Berrino, Paolo Guglielmi, Simone Carradori, Guya Diletta Marconi, Jacopo Pizzicannella, Simone Guarnieri, Tiziano Tuccinardi, Giulio Poli, Federico Pepi, Anna Troiani, Chiara Salvitti, Alessia Di Noi, Michele Coluccia, Giorgio Buttitta, Virginia Pontecorvi, Arianna Granese, Paola Chimenti, Daniela Secci, Anel Petzer, Jacobus Petrus Petzer, Francesca Diomede
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-03-01
Col·lecció:	Antioxidants
Matèries:	benzothiophene Parkinson’s disease neuroprotection ROS docking monoamine oxidase
Accés en línia:	https://www.mdpi.com/2076-3921/15/3/346
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