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Urine proteomics defines an immune checkpoint-associated nephritis signature

Immune checkpoint inhibitor (ICI) therapy is a cornerstone treatment for many cancers, but it can induce severe immunotoxicity, including acute interstitial nephritis (AIN). Currently, kidney biopsy is required to differentiate ICI-AIN from other causes of acute kidney injury (AKI). However, this in...

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Autors principals: Cassian Yee, Jamie S Lin, James P Long, Shailbala Singh, Yanlan Dong
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2025-01-01
Col·lecció:Journal for ImmunoTherapy of Cancer
Accés en línia:https://jitc.bmj.com/content/13/1/e010680.full
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