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Improved mechanical performance and enzymatic stability of crosslinked dry amniotic membrane by spraying

Abstract Human amniotic membrane (AM), a valuable natural biomaterial, is increasingly used in clinical applications. However, its limited mechanical strength and rapid degradation restrict broader use. To address these limitations, we developed a spray-applied crosslinking method for dry AM. A spra...

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Principais autores: Yue’e Wang, Liyang Cao, Haina He, Arooj Khabbir, Chun Hu, Renping Liu, Yang Lei
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-04-01
Serier:Collagen and Leather
Fag:
Dry amniotic membrane
Spray-crosslinked
EDC/NHS crosslinking system
Mechanical strength
Anti-enzymatic degradation
Online adgang:https://doi.org/10.1186/s42825-026-00241-0
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