Discovery of quality markers of Meconopsis quintuplinervia based on an absorption-based metabolite approach and rapid quantification using polarity-switching UPLC-QQQ-MS/MS

BackgroundMeconopsis quintuplinervia Regel (MQ) is a traditional Chinese medicine (TCM) used for clearing liver and lung heat in Tibetan medicine for over a thousand years. However, the lack of quality markers that correlate with pharmacological actions and absorption in vivo limits the safety and e...

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Hlavní autoři:	Yifan Tian, Yuan Liu, Yuanlin Kong, Limin Li, Zhengming Yang, Wenbin Li, Qiang Li, Chaoqin Ren, Wenxia Sun, Yanfei Huang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-12-01
Edice:	Frontiers in Pharmacology
Témata:	traditional Chinese medicine Meconopsis quintuplinervia Regel quality markers metabolism LC-MS content determination
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1474768/full
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