Hedgehog and PI3K/Akt/mTOR Signaling Pathways Involvement in Leukemic Malignancies: Crosstalk and Role in Cell Death

The Hedgehog (Hh) and PI3K/Akt/mTOR signaling pathways play a pivotal role in driving the initiation and progression of various cancers, including hematologic malignancies such as acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and chronic lymphocyti...

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Bibliographische Detailangaben
Hauptverfasser: Mariaconcetta Sicurella, Marica De Chiara, Luca Maria Neri
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-02-01
Schriftenreihe:Cells
Schlagworte:
Hedgehog (Hh) signaling
PI3K/Akt/mTOR pathway
leukemia
autophagy
apoptosis
Online Zugang:https://www.mdpi.com/2073-4409/14/4/269
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