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Sex differences in adenosine deaminase activity associate with disparities in SARS-CoV-2 innate immunity

Summary: Females demonstrate elevated type-I interferon production and a stronger antiviral immune response; however, the mechanisms underlying sex-based differences in antiviral immunity are incompletely understood. We previously reported that low adenosine deaminase (ADA) activity perturbs the met...

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Principais autores: Priyanka Saminathan, Ian T. Mathews, Ahmad Alimadadi, Kai Fung, Kiyokazu Kakugawa, Leo A.B. Joosten, Mihai G. Netea, Mohit Jain, Susan Cheng, Catherine C. Hedrick, Sonia Sharma
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-05-01
Serier:iScience
Fag:
Immunology
Virology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004225006790
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